A "macrodose" (typically 2.5 grams or more) is a profound psychedelic experience. Proper preparation is the key to a positive journey.Set and Setting"Set" is your mindset. Enter the experience with a clear intention and a calm mind. "Setting" is your environment. Choose a safe, comfortable, and familiar space, preferably in nature or a cozy home.The ChecklistClear your schedule for the entire day.Prepare a playlist of calming, instrumental music.Have water, light fruits, and tissues nearby.Ensure you have a trusted, sober trip sitter if it is your first time.