Dr. James Fadiman, a pioneer in psychedelic research, popularized a specific scheduling method for microdosing: one day on, two days off.Why the 1-On, 2-Off Schedule?Day 1 is the microdose day. Day 2 is the "afterglow" day, where you still feel subtle benefits. Day 3 is a reset day to prevent your brain's serotonin receptors from building a tolerance. This cycle ensures long-term effectiveness.Stick to this protocol for 4 to 8 weeks, then take a two-week break to reset your tolerance completely.