Combining mushrooms and cannabis is a popular practice, but it can drastically alter your experience. When used intentionally, it can create a profound synergistic effect.How They InteractCannabis can massively amplify the visual and mental effects of psilocybin. Even a small amount of weed during the peak of a trip can send you into a much deeper headspace.Best PracticesIf you want to combine them, it is highly recommended to consume the cannabis *after* the mushrooms have fully peaked. Using a small amount of CBD-dominant flower can also help smooth out the come-up and reduce anxiety without overwhelming the trip.